Infectious Disease Abbreviations

92 abbreviations · part of Medical Abbreviations

Abbreviations for infections and the organisms that cause them, HIV care, sexually transmitted infections, viral hepatitis, tuberculosis, drug-resistant bacteria, hospital infection control and adult vaccines. They appear in infectious disease consult notes, microbiology reports, public health alerts and infection prevention dashboards. Organism names are conventionally italicized in full (Staphylococcus aureus) and abbreviated after first use (S. aureus), while surveillance terms such as CLABSI and CAUTI follow CDC National Healthcare Safety Network definitions.

AbbreviationStands forDescription
ACIPAdvisory Committee on Immunization PracticesFederal advisory committee that recommends how vaccines licensed by the FDA should be used in the US civilian population, including which ages and groups should receive…
AIDSAcquired immunodeficiency syndromeThe most advanced stage of HIV infection, diagnosed when the CD4 count falls below 200 cells/mm3 or an AIDS-defining illness occurs, such as Pneumocystis pneumonia…
AMRAntimicrobial resistanceAbility of bacteria, viruses, fungi and parasites to survive medicines designed to kill them, driven by overuse and misuse of antimicrobials in humans and animals.
ARFAcute rheumatic feverAutoimmune inflammatory illness that follows untreated group A streptococcal throat infection by two to four weeks, affecting the joints, heart, skin and brain.
ARTAntiretroviral therapyCombination of medicines from at least two drug classes that suppresses HIV replication, restores immune function and prevents transmission.
ASPAntimicrobial stewardship programCoordinated hospital or clinic program, usually led by an infectious disease physician and pharmacist, that improves antibiotic use through audits, feedback, approval…
BCGBacillus Calmette-GuérinLive attenuated vaccine made from Mycobacterium bovis, given at birth in many countries to protect young children against severe forms of tuberculosis such as TB…
BSIBloodstream infectionInfection in which bacteria or fungi are found in blood cultures with corresponding illness.
C. diffClostridioides difficileSpore-forming gut bacterium whose toxins cause diarrhea and colitis, usually after antibiotics disrupt normal gut flora.
CD4Cluster of differentiation 4 (CD4 T-cell count)Count of helper T lymphocytes in the blood, normally about 500–1,500 cells/mm3, used to stage HIV infection and decide on preventive treatment.
CDIClostridioides difficile infectionClinical and surveillance term for diarrhea or colitis with a positive C. difficile toxin or molecular test.
CMVCytomegalovirusCommon herpesvirus that infects most adults, usually without symptoms, and stays latent for life.
COVID-19Coronavirus disease 2019Disease caused by the SARS-CoV-2 coronavirus, ranging from no symptoms to severe pneumonia, blood clots and multiorgan failure, with lasting symptoms (long COVID) in…
CRABCarbapenem-resistant Acinetobacter baumanniiHighly drug-resistant Acinetobacter that survives for long periods on hospital surfaces and causes ventilator-associated pneumonia, bloodstream and wound infections…
CRECarbapenem-resistant EnterobacteralesGut bacteria such as Klebsiella pneumoniae and E. coli that resist carbapenems, the antibiotics of last resort for many infections, often by producing carbapenemase…
CTChlamydia trachomatisBacterium causing chlamydia, the most commonly reported bacterial STI in the US, which is often silent but can lead to pelvic inflammatory disease, ectopic pregnancy…
DAADirect-acting antiviralClass of oral hepatitis C drugs that block specific viral proteins (NS3/4A protease, NS5A or NS5B polymerase), curing most infections with few side effects.
DOTDirectly observed therapyStrategy in which a health worker watches a patient take each dose of TB medicine, in person or by video, to ensure adherence and prevent drug resistance.
E. coliEscherichia coliGut bacterium that is mostly harmless but includes strains causing the majority of urinary tract infections, many bloodstream infections and neonatal meningitis, as…
EBVEpstein-Barr virusHerpesvirus that infects more than 90 percent of adults worldwide and causes infectious mononucleosis, with fever, sore throat, swollen lymph nodes and fatigue…
EPTExpedited partner therapyPractice of giving patients medication or a prescription to deliver to their sex partners, without the partners being examined, to treat chlamydia, gonorrhea or…
ESBLExtended-spectrum beta-lactamaseBacterial enzymes, most often produced by E. coli and Klebsiella, that break down penicillins and most cephalosporins, including ceftriaxone.
FUOFever of unknown originProlonged fever of 38.3°C (101°F) or higher on several occasions, lasting at least three weeks, without a diagnosis after an appropriate initial evaluation.
GASGroup A StreptococcusStreptococcus pyogenes, the cause of strep throat, scarlet fever, impetigo and cellulitis, and of rare but life-threatening invasive infections such as necrotizing…
GCGonococcus (gonorrhea)Clinical shorthand for Neisseria gonorrhoeae, the bacterium that causes gonorrhea, an STI of the urethra, cervix, rectum and throat.
GNRGram-negative rodsMicrobiology description of rod-shaped bacteria that stain pink with Gram stain, including E. coli, Klebsiella, Pseudomonas, Enterobacter and Proteus.
GPCGram-positive cocciMicrobiology description of round bacteria that stain purple on Gram stain.
H1N1Influenza A virus subtype H1N1Subtype of influenza A named for its hemagglutinin type 1 and neuraminidase type 1 surface proteins.
H5N1Influenza A virus subtype H5N1Highly pathogenic avian influenza virus that causes massive outbreaks in wild birds and poultry and occasionally infects mammals and humans.
HAARTHighly active antiretroviral therapyTerm coined in the mid-1990s for the then-new combinations of three or more antiretroviral drugs, including protease inhibitors, that dramatically cut AIDS deaths.
HAPHospital-acquired pneumoniaPneumonia that develops 48 hours or more after hospital admission and was not incubating at the time of admission, excluding patients on mechanical ventilation, whose…
HAVHepatitis A virusVirus spread by the fecal-oral route through contaminated food, water or close contact, causing acute hepatitis with fever, nausea and jaundice.
HBsAgHepatitis B surface antigenProtein on the surface of hepatitis B virus whose presence in blood indicates current infection, either acute or chronic.
HBVHepatitis B virusDNA virus spread through blood, sex and from mother to baby at birth, causing acute or chronic hepatitis.
HCVHepatitis C virusBloodborne RNA virus that causes chronic hepatitis in most people infected, often silently for decades, leading to cirrhosis and liver cancer.
HIVHuman immunodeficiency virusRetrovirus that infects CD4 T cells and, without treatment, gradually destroys the immune system, leading to AIDS.
hMPVHuman metapneumovirusRespiratory virus related to RSV that causes colds, bronchiolitis and pneumonia, mainly in young children, older adults and people with weakened immunity.
HPVHuman papillomavirusGroup of more than 200 related viruses, about 40 of which infect the genital area; it is the most common sexually transmitted infection, and most sexually active people…
HSVHerpes simplex virusVirus with two types that cause lifelong infection with recurring outbreaks of blisters and sores: HSV-1 usually affects the mouth (cold sores) and HSV-2 the genitals…
HZHerpes zosterPainful, blistering rash caused by reactivation of the varicella-zoster virus, usually confined to one dermatome on one side of the body.
IDSAInfectious Diseases Society of AmericaProfessional society representing infectious disease physicians, scientists and other specialists, best known for its clinical practice guidelines on infections such as…
IGRAInterferon-gamma release assayBlood test for TB infection that measures interferon-gamma released by a person's white cells when exposed to TB-specific proteins.
IIVInactivated influenza vaccineInjected flu vaccine containing killed or split virus components, recommended every year for everyone six months and older.
ILIInfluenza-like illnessSurveillance definition of a fever of 100°F (37.8°C) or higher together with cough or sore throat, without another known cause.
IRISImmune reconstitution inflammatory syndromeParadoxical worsening of an infection, or unmasking of a hidden one, after antiretroviral therapy restores the immune system in people with advanced HIV.
KSKaposi sarcomaCancer of the cells lining blood and lymph vessels, caused by human herpesvirus 8 (HHV-8), that produces purple, red or brown patches and nodules on the skin, mouth and…
LAIVLive attenuated influenza vaccineNasal spray flu vaccine (FluMist) containing weakened viruses that replicate in the cooler nose but not the lungs.
LTBILatent tuberculosis infectionInfection with TB bacteria that the immune system holds in check, producing no symptoms and no spread to others.
MACMycobacterium avium complexGroup of environmental nontuberculous mycobacteria that cause disseminated infection in advanced HIV (CD4 below 50) and chronic lung disease in people with…
MDR-TBMultidrug-resistant tuberculosisTuberculosis resistant to at least isoniazid and rifampin, the two most powerful first-line drugs.
MDROMultidrug-resistant organismUmbrella term for bacteria resistant to several classes of antibiotics, including MRSA, VRE, CRE, ESBL producers and resistant Pseudomonas and Acinetobacter.
MERSMiddle East respiratory syndromeSevere respiratory illness caused by MERS-CoV, a coronavirus first identified in Saudi Arabia in 2012 and acquired mainly from dromedary camels.
MICMinimum inhibitory concentrationLowest concentration of an antibiotic or antifungal that prevents visible growth of a microorganism in the laboratory.
MRSAMethicillin-resistant Staphylococcus aureusStaph strains resistant to methicillin and nearly all other beta-lactam antibiotics, including penicillins and most cephalosporins.
MSMMen who have sex with menEpidemiologic term that describes sexual behavior rather than identity, used in HIV and STI surveillance, prevention guidelines and research.
MSSAMethicillin-susceptible Staphylococcus aureusStaph aureus strains that remain susceptible to anti-staphylococcal beta-lactams.
N95N95 filtering facepiece respiratorTight-fitting disposable respirator certified by the US National Institute for Occupational Safety and Health (NIOSH) to filter at least 95 percent of airborne…
NHSNNational Healthcare Safety NetworkCDC surveillance system used by tens of thousands of US hospitals, dialysis centers, nursing homes and other facilities to report healthcare-associated infections…
NSTINecrotizing soft tissue infectionRapidly spreading infection that destroys skin, fat, fascia or muscle, including necrotizing fasciitis and Fournier gangrene.
NTMNontuberculous mycobacteriaEnvironmental mycobacteria other than the tuberculosis complex and leprosy bacillus, found in soil and water, that cause chronic lung infections in people with…
OIOpportunistic infectionInfection caused by organisms that rarely make healthy people seriously ill but exploit a weakened immune system, as in advanced HIV, transplant recipients and…
OPATOutpatient parenteral antimicrobial therapyDelivery of intravenous antibiotics outside the hospital, at home, in infusion centers or skilled nursing facilities, typically through a PICC line.
PAPRPowered air-purifying respiratorBattery-powered respirator that blows filtered air into a loose-fitting hood or tight facepiece, providing high protection against airborne infections without fit…
PCPPneumocystis pneumoniaFungal lung infection caused by Pneumocystis jirovecii, seen in people with CD4 counts below 200, transplant recipients and patients on long-term steroids.
PEPPost-exposure prophylaxisShort course of antiretroviral drugs started within 72 hours after a possible HIV exposure, such as a needlestick injury, sexual assault or condom failure, to prevent…
PHNPostherpetic neuralgiaPersistent nerve pain lasting three months or more in the area of a shingles rash after it has healed.
PLWHPeople living with HIVPerson-first term used in public health, research and clinical guidelines for people who have HIV infection.
PPDPurified protein derivative (tuberculin skin test)Extract of tuberculin injected into the skin of the forearm to test for TB infection; the raised, hardened area (induration) is measured 48–72 hours later.
PPSV2323-valent pneumococcal polysaccharide vaccinePneumococcal vaccine (Pneumovax 23) covering 23 serotypes of Streptococcus pneumoniae, made from purified capsular sugars.
PrEPPre-exposure prophylaxisHIV prevention method in which HIV-negative people take antiretroviral medicine before possible exposure, either as a daily pill or long-acting injection.
RMSFRocky Mountain spotted feverTick-borne bacterial infection caused by Rickettsia rickettsii, producing fever, headache and a rash that often starts at the wrists and ankles and spreads to the palms…
RSVRespiratory syncytial virusCommon respiratory virus that causes cold-like illness in most people but is the leading cause of bronchiolitis and pneumonia in US infants and a major cause of…
RVPRespiratory viral panelMultiplex PCR test, usually on a nasopharyngeal swab, that detects many respiratory viruses and some bacteria at once, such as influenza, RSV, SARS-CoV-2, rhinovirus…
RZVRecombinant zoster vaccineNon-live shingles vaccine (Shingrix) given as two doses two to six months apart to adults 50 and older and to immunocompromised adults 19 and older.
S. aureusStaphylococcus aureusBacterium carried in the nose or on the skin of about a third of people that causes boils, cellulitis, abscesses, pneumonia, bone infections, endocarditis and toxic…
SARSSevere acute respiratory syndromeCoronavirus disease that emerged in southern China in late 2002 and spread to about 29 countries in 2003, causing roughly 8,000 cases and 774 deaths before being…
SARS-CoV-2Severe acute respiratory syndrome coronavirus 2The coronavirus that causes COVID-19, first identified in Wuhan, China, in late 2019.
SSTISkin and soft tissue infectionBroad category covering infections of the skin and underlying tissues, from impetigo, cellulitis and erysipelas to abscesses, wound infections and necrotizing infections.
STDSexually transmitted diseaseTraditional term for illnesses spread through sexual contact, still widely used by the public and in clinic names and insurance forms.
STECShiga toxin-producing Escherichia coliGroup of E. coli strains, the best known being O157:H7, that produce Shiga toxins and cause bloody diarrhea, abdominal cramps and, in about 5–10 percent of cases…
STISexually transmitted infectionInfection passed mainly through sexual contact, including chlamydia, gonorrhea, syphilis, trichomoniasis, HPV, herpes and HIV.
SVRSustained virologic responseUndetectable hepatitis C RNA at a set time after completing treatment, usually 12 weeks (SVR12), which is considered a virologic cure.
TBTuberculosisInfectious disease caused by Mycobacterium tuberculosis that spreads through the air and usually affects the lungs, causing chronic cough, fever, night sweats and…
TdTetanus and diphtheria toxoids vaccineAdult booster vaccine against tetanus and diphtheria recommended every 10 years after the childhood series, and sooner for dirty or major wounds if more than five years…
TdapTetanus, diphtheria and acellular pertussis vaccineBooster vaccine for adolescents and adults that protects against tetanus, diphtheria and whooping cough.
TSSToxic shock syndromeRapidly progressive, life-threatening illness caused by toxins from Staphylococcus aureus or group A Streptococcus that act as superantigens.
U=UUndetectable equals untransmittablePublic health message, backed by large studies, that a person with HIV who keeps an undetectable viral load on treatment does not transmit the virus sexually.
VAERSVaccine Adverse Event Reporting SystemUS national early-warning system, co-managed by the CDC and FDA since 1990, that collects reports of health problems occurring after vaccination.
VLViral loadAmount of virus in the blood, measured by PCR as copies per milliliter, used to monitor HIV, hepatitis B and C, and CMV infection.
VREVancomycin-resistant EnterococcusEnterococci, usually Enterococcus faecium, that have acquired resistance to vancomycin.
VZVVaricella-zoster virusHerpesvirus that causes chickenpox (varicella) on first infection and later, after lying dormant in nerve ganglia, can reactivate as shingles (herpes zoster).
WNVWest Nile virusMosquito-borne flavivirus, spread mainly by Culex mosquitoes that feed on infected birds, and the leading cause of mosquito-borne disease in the continental US.

More medical abbreviations