BL/BLI

Medical abbreviation · Drug Class

BL/BLI
Stands forBeta-lactam/beta-lactamase inhibitor
CategoriesMedical

BL/BLI stands for Beta-lactam/beta-lactamase inhibitor, a drug class abbreviation.

Antibiotic combinations pairing a penicillin or cephalosporin with a drug that blocks bacterial beta-lactamase enzymes, such as amoxicillin-clavulanate, ampicillin-sulbactam, piperacillin-tazobactam and ceftazidime-avibactam.

Example: ESBL bacteremia: BL/BLI not preferred; switch pip-tazo to meropenem.

Usage notes

The inhibitor protects the antibiotic from enzymes that would otherwise destroy it. Newer combinations such as ceftazidime-avibactam (2015) and meropenem-vaborbactam (2017) target carbapenem-resistant Enterobacterales. The MERINO trial (2018) found pip-tazo inferior to meropenem for ESBL bloodstream infections, shaping current guidance.

More drug class abbreviations

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  • ASO – Antisense oligonucleotide
  • ATD – Antithyroid drug
  • BAS – Bile acid sequestrant
  • BB – Beta-blocker
  • BiTE – Bispecific T-cell engager
  • BTKi – Bruton tyrosine kinase inhibitor
  • BZD – Benzodiazepine
  • BZRA – Benzodiazepine receptor agonist
  • CAI – Carbonic anhydrase inhibitor
  • CCB – Calcium channel blocker
  • CDK4/6i – Cyclin-dependent kinase 4/6 inhibitor

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Edited by the AbbreviationList.com team. Spotted an error or a missing meaning? Contact us.

This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.