PBC

Abbreviation with 2 meanings

PBC
Stands forPrimary biliary cholangitis
Meanings2
CategoriesMedical, Business & Finance

PBC has two meanings. It stands for Primary biliary cholangitis (gastroenterology) or Public benefit corporation (company type).

Meanings of PBC at a glance

#PBC stands forContext
1Primary biliary cholangitisMedical › Gastroenterology
2Public benefit corporationBusiness & Finance › Company Type

1. Primary biliary cholangitis

Medical · Gastroenterology Abbreviations

Autoimmune disease that slowly destroys the small bile ducts inside the liver, mostly in middle-aged women. Diagnosis rests on a raised alkaline phosphatase and antimitochondrial antibodies; ursodeoxycholic acid is first-line, with obeticholic acid or newer PPAR agonists for inadequate responders.

Example: AMA positive, ALP 2.5 times normal, fatigue and pruritus: PBC, start ursodiol 13–15 mg/kg/day.

Renamed in 2015 from primary biliary cirrhosis, because most patients diagnosed today never develop cirrhosis and the old name carried stigma. Antimitochondrial antibodies are found in about 95 percent of cases. Elafibranor and seladelpar received accelerated FDA approval in 2024 as second-line treatments.

2. Public benefit corporation

Business & Finance · Company Type Abbreviations

US for-profit corporation whose charter commits it to pursue one or more stated public benefits, such as environmental or social goals, alongside shareholder returns. Directors must balance shareholders' financial interests with the stated benefit and the interests of those affected by the company's conduct.

Example: The outdoor retailer reincorporated as a Delaware PBC with a mission to protect public lands.

Delaware added PBCs to its corporate law in 2013, and many states have similar "benefit corporation" statutes. Companies organized as PBCs include Anthropic and Allbirds, which went public as a PBC in 2021. PBC status is a legal form and differs from B Corp certification, which is awarded by the nonprofit B Lab.

More gastroenterology abbreviations

  • NG – Nasogastric
  • NVD – Nausea, vomiting and diarrhea
  • OGD – Oesophagogastroduodenoscopy
  • OLT – Orthotopic liver transplantation
  • PEG – Percutaneous endoscopic gastrostomy
  • POEM – Peroral endoscopic myotomy
  • PSC – Primary sclerosing cholangitis
  • PTC – Percutaneous transhepatic cholangiography

See all 85 gastroenterology abbreviations →

More company type abbreviations

  • OPC – One person company
  • Oy – Osakeyhtiö (limited company)
  • Oyj – Julkinen osakeyhtiö (public limited company)
  • PA – Professional association
  • PC – Professional corporation
  • PCL – Public company limited
  • PJSC – Public joint-stock company
  • PLC – Public limited company

See all 78 company type abbreviations →

This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.