SCT
Abbreviation with 2 meanings
| Stands for | Sickle cell trait |
|---|---|
| Meanings | 2 |
| Categories | Medical |
SCT has two meanings. It stands for Sickle cell trait (hematology and oncology) or Stem cell transplant (hematology and oncology).
Meanings of SCT at a glance
| # | SCT stands for | Context |
|---|---|---|
| 1 | Sickle cell trait | Medical › Hematology and Oncology |
| 2 | Stem cell transplant | Medical › Hematology and Oncology |
1. Sickle cell trait
Medical · Hematology and Oncology Abbreviations
Carrier state in which a person inherits one sickle hemoglobin gene and one normal gene, usually causing no symptoms. It affects about 1 in 13 Black or African American babies in the US and is common in people with ancestry from malaria-endemic regions.
Example: Newborn screen shows FAS pattern consistent with SCT; parents counseled on genetic implications.
The trait protects against severe malaria, which explains its high frequency in parts of Africa, the Mediterranean, the Middle East and India. Although usually benign, it is linked to exertional collapse under extreme conditions, blood in the urine and a rare kidney cancer, renal medullary carcinoma. The NCAA began requiring trait status for Division I athletes in 2010. In transplant medicine SCT means stem cell transplant.
2. Stem cell transplant
Medical · Hematology and Oncology Abbreviations
General term for transplanting blood-forming stem cells, used interchangeably with bone marrow transplant and HSCT in clinical notes and patient education. Autologous SCT uses the patient's own cells, while allogeneic SCT uses donor cells.
Example: Myeloma in VGPR after induction; collecting stem cells for SCT in May.
Peripheral blood stem cells are collected by apheresis after mobilization with growth factors such as G-CSF, sometimes with plerixafor. Recovery of white cells, called engraftment, typically occurs about two to three weeks after infusion. In newborn screening and hematology SCT can also mean sickle cell trait, so the context of the note matters.
Related abbreviations
More hematology and oncology abbreviations
- RECIST – Response Evaluation Criteria in Solid Tumors
- RT – Radiation therapy
- SBRT – Stereotactic body radiation therapy
- SCA – Sickle cell anemia
- SCD – Sickle cell disease
- SCLC – Small cell lung cancer
- SD – Stable disease
- SEER – Surveillance, Epidemiology, and End Results Program
- TACO – Transfusion-associated circulatory overload
- TKI – Tyrosine kinase inhibitor
- TLS – Tumor lysis syndrome
- TMA – Thrombotic microangiopathy
See all 144 hematology and oncology abbreviations →
This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.