TKI
Medical abbreviation · Drug Class
| Stands for | Tyrosine kinase inhibitor |
|---|---|
| Categories | Medical |
TKI stands for Tyrosine kinase inhibitor, a drug class abbreviation.
Small-molecule targeted cancer drugs, with generic names ending in "-tinib", that block overactive signaling enzymes, such as imatinib for chronic myeloid leukemia and osimertinib for EGFR-mutated lung cancer. Most are oral tablets taken daily.
Example: TKI dasatinib: stop pantoprazole; use famotidine 2 hours after the dose if needed.
Usage notes
Imatinib, approved in 2001, turned chronic myeloid leukemia into a manageable chronic illness. Many TKIs are broken down by CYP3A4 and have serious interactions, some need stomach acid to absorb, and some must be taken on an empty stomach. Pharmacist review of every new prescription is standard because adherence and interactions strongly affect results.
Related abbreviations
More drug class abbreviations
- SLIT – Sublingual immunotherapy
- SMART – Single maintenance and reliever therapy
- SNRI – Serotonin-norepinephrine reuptake inhibitor
- SSRI – Selective serotonin reuptake inhibitor
- SU – Sulfonylurea
- TCA – Tricyclic antidepressant
- TNFi – Tumor necrosis factor inhibitor
- TPO-RA – Thrombopoietin receptor agonist
- TZD – Thiazolidinedione
- UFH – Unfractionated heparin
- VKA – Vitamin K antagonist
- VMAT2i – Vesicular monoamine transporter 2 inhibitor
See all 113 drug class abbreviations →
This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.