mRNA

Science & Engineering abbreviation · Biology

mRNA
Stands forMessenger RNA
CategoriesScience & Engineering

mRNA stands for Messenger RNA, a biology abbreviation.

RNA copy of a gene that carries protein-building instructions from DNA in the nucleus to ribosomes in the cytoplasm, where each three-letter codon specifies an amino acid. Synthetic mRNA is the basis of the Pfizer-BioNTech and Moderna COVID-19 vaccines, which instruct cells to make a harmless piece of viral protein.

Example: The vaccine's mRNA is broken down by the body within days and never enters the cell nucleus.

Usage notes

Sydney Brenner, François Jacob and Matthew Meselson demonstrated the existence of messenger RNA in 1961. Katalin Karikó and Drew Weissman found that swapping uridine for modified nucleosides keeps synthetic mRNA from triggering harmful inflammation, earning the 2023 Nobel Prize in Physiology or Medicine. Written with a lowercase m and pronounced "em-R-N-A."

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