LAI
Medical abbreviation · Drug Class
| Stands for | Long-acting injectable |
|---|---|
| Categories | Medical |
LAI stands for Long-acting injectable, a drug class abbreviation.
Depot formulation that releases a drug slowly for weeks to months after a single injection, most often antipsychotics such as paliperidone palmitate, aripiprazole, risperidone, haloperidol decanoate and fluphenazine decanoate. Buprenorphine and HIV drugs also come as LAIs.
Example: LAI paliperidone palmitate 234 mg IM day 1, 156 mg day 8, then monthly.
Usage notes
LAIs improve adherence and reduce relapse in schizophrenia. Intervals now range from every two weeks to every six months. Olanzapine pamoate requires a three-hour observation after each injection under a REMS program because of post-injection delirium and sedation syndrome. Oral tolerability is usually confirmed before the first depot dose.
Related abbreviations
More drug class abbreviations
- IMiD – Immunomodulatory imide drug
- INCS – Intranasal corticosteroids
- INSTI – Integrase strand transfer inhibitor
- JAKi – Janus kinase inhibitor
- LABA – Long-acting beta2-agonist
- LABA/LAMA – Long-acting beta-agonist and long-acting muscarinic antagonist…
- LAMA – Long-acting muscarinic antagonist
- LMWH – Low-molecular-weight heparin
- LTRA – Leukotriene receptor antagonist
- mAb – Monoclonal antibody
- MAOI – Monoamine oxidase inhibitor
- MHT – Menopausal hormone therapy
See all 113 drug class abbreviations →
This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.