GPI

Medical abbreviation · Drug Class

GPI
Stands forGlycoprotein IIb/IIIa inhibitor
CategoriesMedical

GPI stands for Glycoprotein IIb/IIIa inhibitor, a drug class abbreviation.

IV antiplatelet drugs, eptifibatide and tirofiban, that block the final common pathway of platelet aggregation. They are used selectively during percutaneous coronary intervention, especially with large clot burden.

Example: GPI eptifibatide bolus given in the cath lab for no-reflow.

Usage notes

Abciximab, the first agent and a monoclonal antibody fragment, is no longer marketed in the US. Bleeding and a sudden fall in platelet count are the main risks. Routine use has declined since potent oral P2Y12 inhibitors became standard. Also written GP IIb/IIIa inhibitor.

More drug class abbreviations

  • FGA – First-generation antipsychotic
  • FQ – Fluoroquinolone
  • GC – Glucocorticoid
  • GIP/GLP-1 RA – Glucose-dependent insulinotropic polypeptide and glucagon-like…
  • GLP-1 RA – Glucagon-like peptide-1 receptor agonist
  • GnRHa – Gonadotropin-releasing hormone agonist
  • H2RA – Histamine-2 receptor antagonist
  • HRT – Hormone replacement therapy
  • ICI – Immune checkpoint inhibitor
  • ICS – Inhaled corticosteroid
  • ICS/LABA – Inhaled corticosteroid and long-acting beta-agonist combination
  • IMiD – Immunomodulatory imide drug

See all 113 drug class abbreviations →

Edited by the AbbreviationList.com team. Spotted an error or a missing meaning? Contact us.

This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.