TZD

Medical abbreviation · Drug Class

TZD
Stands forThiazolidinedione
CategoriesMedical

TZD stands for Thiazolidinedione, a drug class abbreviation.

Insulin-sensitizing diabetes drugs, pioglitazone and rosiglitazone, that activate the PPAR-gamma receptor in fat and muscle. Also called glitazones, they lower glucose durably and pioglitazone improves fatty liver disease.

Example: Add TZD (pioglitazone 15 mg daily); monitor weight and edema.

Usage notes

The first, troglitazone, was withdrawn in 2000 because of liver failure. TZDs cause fluid retention and carry a boxed warning against use in symptomatic heart failure; weight gain and fractures are also concerns. Rosiglitazone was heavily restricted in 2010 over heart attack concerns, restrictions the FDA later lifted.

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Edited by the AbbreviationList.com team. Spotted an error or a missing meaning? Contact us.

This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.