HSIL

Medical abbreviation · Obstetrics & Gynecology

HSIL
Stands forHigh-grade squamous intraepithelial lesion
CategoriesMedical

HSIL stands for High-grade squamous intraepithelial lesion, an obstetrics & gynecology abbreviation.

Pap result indicating moderate to severe cell changes with a substantial risk of underlying CIN 2 or CIN 3, the true cancer precursors. It requires colposcopy or, in some cases, immediate excisional treatment.

Example: Pap HSIL with HPV 16 positive; expedited LEEP offered per ASCCP risk estimate.

Usage notes

ASCCP guidelines allow treatment without a confirming biopsy when the estimated risk of CIN 3 or worse is high. HSIL in pregnancy is evaluated with colposcopy, but treatment is usually delayed until after delivery. Pronounced as letters or "AITCH-sil".

More obstetrics & gynecology abbreviations

  • GCT – Glucose challenge test
  • GSM – Genitourinary syndrome of menopause
  • GTPAL – Gravida, term, preterm, abortions, living
  • HELLP – Hemolysis, elevated liver enzymes and low platelets
  • HG – Hyperemesis gravidarum
  • HRT – Hormone replacement therapy
  • ICP – Intrahepatic cholestasis of pregnancy
  • ICSI – Intracytoplasmic sperm injection
  • IOL – Induction of labor
  • IUD – Intrauterine device
  • IUFD – Intrauterine fetal demise
  • IUGR – Intrauterine growth restriction

See all 89 obstetrics & gynecology abbreviations →

This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.