DRI

Abbreviation with 2 meanings

DRI
Stands forDirectly responsible individual
Meanings2
CategoriesBusiness & Finance, Medical

DRI has two meanings. It stands for Directly responsible individual (management & strategy) or Direct renin inhibitor (drug class).

Meanings of DRI at a glance

#DRI stands forContext
1Directly responsible individualBusiness & Finance › Management & Strategy
2Direct renin inhibitorMedical › Drug Class

1. Directly responsible individual

Business & Finance · Management & Strategy Abbreviations

Single person who owns a project, decision or task and is accountable for its outcome, even when many people contribute. Naming a DRI prevents responsibility from becoming diffuse in cross-functional teams.

Example: Every launch blocker in the tracker needs a DRI and a due date by tomorrow's standup.

The practice is associated with Apple and has been adopted by companies such as GitLab, which documents it in its public handbook. A DRI need not do all the work personally but must make sure it gets done and decisions get made.

2. Direct renin inhibitor

Medical · Drug Class Abbreviations

Blood pressure drug class whose only member is aliskiren (Tekturna), which blocks renin, the first step of the renin-angiotensin system. It is rarely used today.

Example: DRI aliskiren discontinued; patient has diabetes and is on lisinopril.

Aliskiren was approved in 2007. The ALTITUDE trial, stopped in 2011, found more strokes, kidney problems and high potassium when aliskiren was added to ACE inhibitors or ARBs in people with diabetes, leading to a contraindication for that combination. Like other renin-angiotensin blockers, it is contraindicated in pregnancy.

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More drug class abbreviations

  • DMARD – Disease-modifying antirheumatic drug
  • DOAC – Direct oral anticoagulant
  • DORA – Dual orexin receptor antagonist
  • DPP-4i – Dipeptidyl peptidase-4 inhibitor
  • DTI – Direct thrombin inhibitor
  • EC – Emergency contraception
  • ERA – Endothelin receptor antagonist
  • ERT – Enzyme replacement therapy

See all 113 drug class abbreviations →

This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.