AC-T
Medical abbreviation · Hematology and Oncology
| Stands for | Adriamycin (doxorubicin) and cyclophosphamide followed by Taxol (paclitaxel) |
|---|---|
| Categories | Medical |
AC-T stands for Adriamycin (doxorubicin) and cyclophosphamide followed by Taxol (paclitaxel), a hematology and oncology abbreviation.
Breast cancer chemotherapy regimen given before or after surgery: four cycles of doxorubicin and cyclophosphamide followed by paclitaxel, either weekly or every two weeks. Dose-dense scheduling every two weeks requires growth factor support.
Example: High-risk node-positive breast cancer: dose-dense AC-T, pegfilgrastim after each AC cycle.
Usage notes
The CALGB 9741 trial (2003) showed that giving the regimen every two weeks instead of three improved survival. Doxorubicin carries a cumulative risk of heart damage, so heart function is checked before treatment. For HER2-positive disease trastuzumab is added during the paclitaxel phase, and for triple-negative disease pembrolizumab is combined with chemotherapy.
Related abbreviations
More hematology and oncology abbreviations
- 7+3 – Seven days of cytarabine plus three days of an anthracycline
- ABVD – Adriamycin (doxorubicin), bleomycin, vinblastine, dacarbazine
- ADAMTS13 – A disintegrin and metalloproteinase with thrombospondin type 1…
- ADC – Antibody-drug conjugate
- AFP – Alpha-fetoprotein
- AIHA – Autoimmune hemolytic anemia
- AJCC – American Joint Committee on Cancer
- ALK – Anaplastic lymphoma kinase
- ALL – Acute lymphoblastic leukemia
- AML – Acute myeloid leukemia
- APL – Acute promyelocytic leukemia
- ASCO – American Society of Clinical Oncology
See all 144 hematology and oncology abbreviations →
This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.