1/2NS

Medical abbreviation · Pharmacy

1/2NS
Stands forHalf-normal saline
CategoriesMedical

1/2NS stands for Half-normal saline, a pharmacy abbreviation.

Hypotonic IV fluid containing 0.45% sodium chloride (77 mEq/L of sodium), used to provide free water and maintenance fluid, for example in hypernatremia or in some diabetic ketoacidosis protocols once circulation is restored.

Example: Change IVF to 1/2NS at 150 mL/h once the corrected sodium is normal.

Usage notes

Also written 0.45NS, 0.45% NaCl or "half NS". Because it is hypotonic, it should not be used to resuscitate shock or in patients at risk of brain swelling. Mixing it with 5% dextrose gives D5 1/2NS. Hospital-acquired hyponatremia linked to hypotonic fluids has shifted practice toward isotonic maintenance fluids.

More pharmacy abbreviations

  • AB – Therapeutically equivalent rating (Orange Book code)
  • ADC – Automated dispensing cabinet
  • ADF – Abuse-deterrent formulation
  • AHFS – American Hospital Formulary Service
  • amp – Ampule
  • ANDA – Abbreviated New Drug Application
  • APhA – American Pharmacists Association
  • API – Active pharmaceutical ingredient
  • aq – Aqueous
  • ARCOS – Automation of Reports and Consolidated Orders System
  • ASHP – American Society of Health-System Pharmacists
  • AWP – Average wholesale price

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This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.