TLE

Medical abbreviation · Neurology

TLE
Stands forTemporal lobe epilepsy
CategoriesMedical

TLE stands for Temporal lobe epilepsy, a neurology abbreviation.

Most common form of focal epilepsy in adults, with seizures arising in the temporal lobe and often preceded by an aura such as déjà vu, fear or a rising sensation in the stomach. Seizures typically involve impaired awareness, lip smacking and hand fumbling.

Example: Seizures begin with an epigastric rising sensation, then staring and lip smacking; MRI shows left mesial temporal sclerosis: TLE.

Usage notes

Mesial temporal sclerosis, scarring of the hippocampus, is the most common underlying lesion. Drug-resistant TLE responds well to surgery: a 2001 randomized trial by Wiebe and colleagues found that surgery made patients seizure-free far more often than medication alone. Laser ablation offers a less invasive surgical option.

More neurology abbreviations

  • SUDEP – Sudden unexpected death in epilepsy
  • Sz – Seizure
  • TBI – Traumatic brain injury
  • TCD – Transcranial Doppler
  • TGA – Transient global amnesia
  • TIA – Transient ischemic attack
  • TM – Transverse myelitis
  • TN – Trigeminal neuralgia
  • tPA – Tissue plasminogen activator (alteplase)
  • TS – Tourette syndrome
  • TTH – Tension-type headache
  • UMN – Upper motor neuron

See all 131 neurology abbreviations →

This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.