ssDNA
Science & Engineering abbreviation · Genetics
| Stands for | Single-stranded DNA |
|---|---|
| Categories | Science & Engineering |
ssDNA stands for Single-stranded DNA, a genetics abbreviation.
DNA consisting of one strand rather than a paired double helix. It occurs in some virus genomes and transiently during DNA replication and repair, and synthetic ssDNA serves as primers, probes and editing templates.
Example: An ssDNA donor template carrying the corrected sequence was co-injected with Cas9.
Usage notes
Viruses with ssDNA genomes include parvoviruses and the adeno-associated viruses (AAV) used as gene therapy vectors. Single-strand binding proteins coat exposed ssDNA in cells to protect it. Heat or alkali separates dsDNA into ssDNA, a process called denaturation or melting.
Related abbreviations
More genetics abbreviations
- sgRNA – Single guide RNA
- shRNA – Short hairpin RNA
- siRNA – Small interfering RNA
- SNP – Single-nucleotide polymorphism
- snRNA – Small nuclear RNA
- SNV – Single-nucleotide variant
- STR – Short tandem repeat
- T2T – Telomere-to-telomere
- TF – Transcription factor
- UTR – Untranslated region
- VNTR – Variable number tandem repeat
- VUS – Variant of uncertain significance