PCC

Medical abbreviation · Drug

PCC
Stands forProthrombin complex concentrate
CategoriesMedical

PCC stands for Prothrombin complex concentrate, a drug abbreviation.

Plasma-derived concentrate of clotting factors II, IX and X (three-factor) or II, VII, IX and X (four-factor), used to rapidly reverse warfarin and, off-label, other anticoagulants in life-threatening bleeding.

Example: INR 4.2 with intracranial bleed: 4F-PCC 50 units/kg IV plus vitamin K 10 mg IV.

Usage notes

Kcentra, the four-factor PCC, was approved in the US in 2013 and reverses warfarin within minutes, much faster than fresh frozen plasma and with far less volume. Vitamin K is given at the same time because PCC effects wear off before warfarin does. PCC carries a boxed warning for arterial and venous clots.

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Edited by the AbbreviationList.com team. Spotted an error or a missing meaning? Contact us.

This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.