NNH

Medical abbreviation · Medical Research

NNH
Stands forNumber needed to harm
CategoriesMedical

NNH stands for Number needed to harm, a medical research abbreviation.

Average number of patients who must receive a treatment for one additional patient to experience a specified harm compared with the control, calculated as 1 divided by the absolute risk increase. It is weighed against the number needed to treat when balancing benefits and risks.

Example: NNT 25 to prevent a stroke versus NNH 200 for a major bleed.

Usage notes

A large NNH is reassuring because the harm is uncommon. Like the NNT, it applies only to a specific outcome, population and time period. Some writers prefer the phrase number needed to treat to harm (NNTH).

More medical research abbreviations

  • MedDRA – Medical Dictionary for Regulatory Activities
  • MeSH – Medical Subject Headings
  • MHRA – Medicines and Healthcare products Regulatory Agency
  • NCT – National Clinical Trial (number)
  • NICE – National Institute for Health and Care Excellence
  • NME – New molecular entity
  • NNT – Number needed to treat
  • NPV – Negative predictive value
  • NS – Not significant (statistically)
  • ODD – Orphan drug designation
  • OHRP – Office for Human Research Protections
  • OR – Odds ratio

See all 94 medical research abbreviations →

This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.