C-II

Medical abbreviation · Pharmacy

C-II
Stands forSchedule II controlled substance
CategoriesMedical

C-II stands for Schedule II controlled substance, a pharmacy abbreviation.

Federal class for drugs with accepted medical use but a high potential for abuse and severe dependence, including most strong opioids (oxycodone, fentanyl, morphine, hydrocodone), stimulants (amphetamine, methylphenidate) and cocaine for topical use.

Example: Hydrocodone combinations moved from C-III to C-II in October 2014.

Usage notes

C-II prescriptions cannot be refilled; prescribers may issue multiple prescriptions totaling up to a 90-day supply with "do not fill before" dates. Pharmacies order C-II stock using DEA Form 222 or its electronic equivalent (CSOS). Labels show a "C" with "II" inside it. Also written CII.

More pharmacy abbreviations

  • BOP – Board of pharmacy
  • BP – British Pharmacopoeia
  • BPMH – Best possible medication history
  • BTC – Behind the counter
  • BUD – Beyond-use date
  • C-I – Schedule I controlled substance
  • C-III – Schedule III controlled substance
  • C-IV – Schedule IV controlled substance
  • C-V – Schedule V controlled substance
  • CACI – Compounding aseptic containment isolator
  • cap – Capsule
  • CD – Controlled delivery

See all 134 pharmacy abbreviations →

This entry is for general education and is not medical advice. Abbreviation use varies between institutions; always confirm in context.